I'm using a Core Duo Mini and I've got to tell you this thing flies. I was concerned about the integrated graphics card but not anymore. PT runs quickly and smoothly with no choppy payback at all. Also was concerned about the Mini's single firewire port since I wanted to use a firewire drive for audio but also play a movie out the firewire port to a monitor using a Canopus. Ended up buying a Newertech V-Stack from OWC and ran audio out the USB 2 port and the movie out firewire...everything ran beautifully with no lags or overloaded system messages. I haven't really pushed plugin usage, since I do sound design, but all my previous sessions with average plug usage have been no problem. I don't anticipate any issues. Sometimes playing a movie from Quicktime itself will be a bit choppy, but within PT there's no problem whatsoever. Very, very very satisfied Mini user here. Mini is Core Duo 100 gig SATA 4200rpm 1 gig ram